ABOUT R2

INNOVATE REPEAT


ABOUT R2 INNOVATIONS

THE COMPANY

R2 Innovations, LLC was founded by Robert L. Senter and Robert E. Matuszewski in 1998 a privately owned, Colorado Limited Liability Company. R2 has arranged an equity partnership with Sievers Biotech for the purpose of utilizing a US patent pending process to convert CBD / cannabis extracted oils into a pharmaceutical grade fine powder for introduction into R2’s metered dose inhaler directed at treating pulmonary diseases.

R2 MISSION

R2’s Mission is to be recognized as a global leader in development and manufacturing of natural cannabinoid medicines to treat specific ailments and diseases.

R2 OBJECTIVE

R2’s objective is to challenge the use of; fluticasone propionate/salmeterol xinafoate, budesonide/formoterol, albuterol/salbutamol, budesonide, fluticasone and formoterol fumarate as the preferred corticosteroid medical treatments in existing metered dose inhalers eliminating adverse side effects, and the threat of death with overdosing for asthmatic, COPD and Emphysema patients.

R2 VISION

R2's Vision is to lead the global marketplace in advanced alternative CBD / cannabis medications with emphasis on respiratory therapies, supported by clinical research, double blind studies and independent lab testing. 

R2 in the works

RESPIRATORY
METERED DOSE INHALER ("MDI")

R2’s AIR™ pressurized, metered-dose inhaler (pMDI) is a customized device that delivers a precise dose of proprietary, cannabidiol and cannabis derived formulations directly into the lungs once activated and inhaled properly.

R2’s pMDI is formulated and manufactured to treat pulmonary diseases which include asthma, COPD and emphysema. Our ability to transition cannabidiol and cannabis derived oils into a pharmaceutical grade fine dry powder for deep lung inhalation with Sievers Biotech CAN-BD bubble dryer overcomes the side effects and overdosing concerns with current corticosteroids and formoterol medications, (US patent pending application # 20160228385).

R2’s pMDI has an aluminum canister manufactured in combination with a specific valve and actuator allowing proprietary powdered cannabidiol and cannabis to be introduced into the canister and pressurized to deliver an aerosol burst of medication to the user once the actuator discharge nozzle is depressed.

Nebulizer

Nebulization will be available as a delivery system for R2’s cannabidiol and cannabis derived formulations utilizing a CO2 extraction method producing the purist cannabidiol oil formulated into a suitable viscosity creating an aerosol mist inhaled directly into the lungs from the mouthpiece of the medical device. 
The nebulization delivery system will be used for administering measured dose, cannabidiol and cannabis derived, solution vials to treat patients suffering from pulmonary diseases with emphasis on asthma.



Vaporizers for medical use

R2’s vaporizer is a delivery system reliant on proprietary cannabidiol and cannabis derived formulations extracted into a purified oil that when inhaled eliminates smoking marijuana cigarettes.

There is no exposure to harmful combustion products using R2’s vaporization device. 

SUB-LINGUAL (Under The Tongue)

Today, many drugs are designed for sub-lingual administration, including cardiovascular drugs, steroids, barbiturates, enzymes and, increasingly, vitamins and minerals.

R2’s cannabidiol and cannabis derived formulations will be offered in a sub-lingual delivery system administered under the tongue. The diffusion of the cannabis formulation into the blood through the tissues under the tongue allows the quickest entrance into the bloodstream.

Our medical CBD / cannabis derivative/formulations for treating different medical conditions will be offered with replaceable cartridges allowing ease of use and accessibility for the patient selecting this method of delivery.

How does it work?
When a chemical comes in contact with the mucous membrane beneath the tongue, it diffuses through it. Because the connective tissue beneath the epithelium contains a profusion of capillaries, the substance then diffuses into them and enters the venous circulation. In contrast, substances absorbed in the intestines are subject to "first-pass metabolism" in the liver before entering the general circulation.

Sublingual administration has certain advantages over oral administration. Being more direct, it is often faster and it ensures that the substance will risk degradation only by salivary enzymes before entering the bloodstream, whereas orally administered drugs must survive passage through the hostile environment of the gastrointestinal tract, 

DIGESTive - edibles / consumables

R2 has developed formulations focusing on medications for consumption orally (gel-pill and tinctures), using non-psychoactive, highly therapeutic compounds from cannabis known as CBD’s, or Cannabinoids. Studies have demonstrated CBD’s benefits in treating a variety of ailments, including, epilepsy, cancer, pain, arthritis, anxiety disorders, and others. CBD can be extracted and processed into a variety of medications, each appropriate for different medical needs.

Medications administered orally can affect the digestive system in a number of different ways. Both prescription and over-the-counter drugs, while usually safe and effective, may create harmful side effects if taken in combination with other medications. It is important that your doctor know about any allergies, sensitivities, as well as other medical conditions you have before taking a new medication.

thc detection & TESTING

R2 is currently engaged in Phase 2 development of a proprietary line of THC, Early Detection Devices (THCEDD's) for consumer, over-the-counter (OTC), medical and law enforcement uses.

R2’s new THC Saliva Test Strips are Accurate – With an accuracy rate of 98% there is very little room for testing error. This means that consumers and law enforcement alike can be extremely confident in the results that are produced from R2 Strips.

R2 saliva drug testing systems are not only accurate, but they are extremely fast. While most clinics take 1-2 days to process and read results, our tests take only five to 10 minutes and require no privacy measures, invasive blood-draws or urine specimens. Unlike these other testing strips and kits, our Saliva Test Strips can be used to test for THC on-the-spot at anytime and anywhere.

Note: Oral fluid testing requires a small sample that is collected under direct supervision without any invasion of privacy. Because collections are observed, oral fluid testing is considered a tamper-resistant screening method in that it’s difficult for a donor to cheat or adulterate their specimen. 

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